Synovial Fluid Mucin

Synovial Fluid Mucin.

Synovial mucin, the characteristic component of synovial fluid, was first isolated in 1846 by Frerichs (1846), who precipitated it from joint fluid by addition of. acetic acid. Its high viscosity and peculiar chemical composition made it a subject of much interest. Frerichs realized that it was a complex of protein and carbohydrate components, but little -additional information was added until ...

A Quantitative Study of Metachromasy in Synovial Fluid and Mucin

SPECTROPHOTOMETRIC MEASUREMENTS ON SYNOVIAL FLUID AND SOLUTIONS OF MUCIN AND HYALURONATE IN THE PRESENCE OF METHYLENE BLUE SHOWED THAT: 1. Dialyzed synovial fluid was not metachromatic. 2. Albumin and gelatin at a concentration of 1 mg. per ml. inhibited the metachromasy of strong chromotropes. 3. Reduction of the protein of synovial fluid by the use of proteolytic enzymes still did not make th...

Electrophoresis studies of human synovial mucin.

A characteristic property of synovial fluids is the formation of a mucin clot when a weak acid is added. The physical character of the clot may be of some aid in the diagnosis of rheumatoid arthritis (Ropes, Bennett, Cobb, Jacox & Jesser, 1957; Ropes & Bauer, 1953). The clot has also been used as a preliminary step in the isolation of hyaluronic acid (Meyer, Smyth & Dawson, 1939) and its hexosa...

Synovial perfusion and synovial fluid solutes.

answer goes back to the cardinal signs of inflammation. The redness and heat of this state relate directly to increased local blood supply, and these critical findings cannot be examined systematically without accurate quantification of flow. Further, the imbalances of vascular permeability and tissue clearance that lead to tissue swelling cannot be evaluated usefully without an understanding o...

Elasticity of synovial fluid.